Publikationen 2017

Age dictates a steroid-resistant cascade of Wnt5a, transglutaminase 2, and leukotrienes in inflamed airways.

Dietz K, de Los Reyes Jiménez M, Gollwitzer ES, Chaker AM, Zissler UM, Rådmark OP, Baarsma HA, Königshoff M, Schmidt-Weber CB, Marsland BJ, Esser-von Bieren J.

J Allergy Clin Immunol.

Bacterial microbiota of the upper respiratory tract and childhood asthma.

Depner M, Ege MJ, Cox MJ, Dwyer S, Walker AW, Birzele LT, Genuneit J, Horak E, Braun-Fahrländer C, Danielewicz H, Maier RM, Moffatt MF, Cookson WO, Heederik D, von Mutius E, Legatzki A.

J Allergy Clin Immunol.

Asthma transition from childhood into adulthood.

Fuchs O, Bahmer T, Rabe KF, von Mutius E.

Lancet Respir Med.  Review

Systemic mastocytosis with generalised skin involvement.

Zink A, Böhner A, Schuch A, Biedermann T, Brockow K.

Lancet. 2017

Enhanced T helper 1 and 2 cytokine responses at birth associate with lower risk of middle ear infections in infancy.

Bergroth E, Roponen M, Karvonen AM, Keski-Nisula L, Remes S, Riedler J, Roduit C, Dalphin JC, Kaulek V, Loss GJ, Lauener R, Hirvonen MR, Genuneit J, Schmaußer-Hechfellner E, Renz H, Pfefferle PI, Krauss-Etschmann S, Schaub B, von Mutius E, Pekkanen J; PASTURE Study Group.

Pediatr Allergy Immunol.

Biomarkers in Allergic Airway Disease: Simply Complex.

Chaker AM, Zissler UM, Wagenmann M, Schmidt-Weber C.

ORL J Otorhinolaryngol Relat Spec.  Review.

Clinical use of adjuvants in allergen-immunotherapy.

Klimek L, Schmidt-Weber CB, Kramer MF, Skinner MA, Heath MD.

Expert Rev Clin Immunol.  Review.

Neurodermitis: Ein Register sorgt für Durchblick.

Biedermann T.

J Dtsch Dermatol Ges.

Anti-inflammatory effects of the petasin phyto drug Ze339 are mediated by inhibition of the STAT pathway.

Steiert SA, Zissler UM, Chaker AM, Esser-von-Bieren J, Dittlein D, Guerth F, Jakwerth CA, Piontek G, Zahner C, Drewe J, Traidl-Hoffmann C, Schmidt-Weber CB, Gilles S.


Chromium(VI) Contact Dermatitis: Getting Closer to Understanding the Underlying Mechanisms of Toxicity and Sensitization!

Buters J, Biedermann T.

J Invest Dermatol.

Do farm-grown lungs breathe better?

Genuneit J, von Mutius E.


Impact of Gliding on the Prevalence of Keratinocyte Carcinoma and its Precursors: A Cross-sectional Study Among Male Pilots in Bavaria.

Zink A, Hänsel I, Rotter M, Spinner CD, Böhner A, Biedermann T.

Acta Derm Venereol. 

Identification of fungal candidates for asthma protection in a large population-based study.

Mueller-Rompa S, Janke T, Schwaiger K, Mayer M, Bauer J, Genuneit J, Braun-Fahrlaender C, Horak E, Boznanski A, von Mutius E, Ege MJ; GABRIELA study group.

Pediatr Allergy Immunol.

Latent class analysis reveals clinically relevant atopy phenotypes in 2 birth cohorts.

Hose AJ, Depner M, Illi S, Lau S, Keil T, Wahn U, Fuchs O, Pfefferle PI, Schmaußer-Hechfellner E, Genuneit J, Lauener R, Karvonen AM, Roduit C, Dalphin JC, Riedler J, Pekkanen J, von Mutius E, Ege MJ; MAS; PASTURE study groups.

J Allergy Clin Immunol.

 Evidence for biochemical barrier restoration: Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis.

Arbiser JL, Nowak R, Michaels K, Skabytska Y, Biedermann T, Lewis MJ, Bonner MY, Rao S, Gilbert LC, Yusuf N, Karlsson I, Fritz Y, Ward NL.

Sci Rep.

The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation.

Schmidt MO, Garman KA, Lee YG, Zuo C, Beck PJ, Tan M, Aguilar-Pimentel JA, Ollert M, Schmidt-Weber C, Fuchs H, Gailus-Durner V, Hrabe de Angelis M; German Mouse Clinic Consortium, Tassi E, Riegel AT, Wellstein A.

J Invest Dermatol.

Effect of Processing Intensity on Immunologically Active Bovine Milk Serum Proteins.

Brick T, Ege M, Boeren S, Böck A, von Mutius E, Vervoort J, Hettinga K.


Immune development and environment: lessons from Amish and Hutterite children.

Ober C, Sperling AI, von Mutius E, Vercelli D.

Curr Opin Immunol.


Pilz AC, Biedermann T, Darsow U.

MMW Fortschr Med.

Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers' children against airway inflammation and colitis.

Frei R, Ferstl R, Roduit C, Ziegler M, Schiavi E, Barcik W, Rodriguez-Perez N, Wirz OF, Wawrzyniak M, Pugin B, Nehrbass D, Jutel M, Smolinska S, Konieczna P, Bieli C, Loeliger S, Waser M, Pershagen G, Riedler J, Depner M, Schaub B, Genuneit J, Renz H, Pekkanen J, Karvonen AM, Dalphin JC, van Hage M, Doekes G, Akdis M, Braun-Fahrländer C, Akdis CA, von Mutius E, O'Mahony L, Lauener RP; Prevention of Allergy Risk factors for Sensitization in Children Related to Farming and Anthroposophic Lifestyle (PARSIFAL) study group; Protection Against Allergy Study in Rural Environments (PASTURE)/Mechanisms of Early Protective Exposures on Allergy Development (EFRAIM) study group.

J Allergy Clin Immunol.

Allergen-specific immunotherapy of Hymenoptera venom allergy - also a matter of diagnosis.

Schiener M, Graessel A, Ollert M, Schmidt-Weber CB, Blank S.

Hum Vaccin Immunother.

Utility of basophil activation testing to assess perioperative anaphylactic reactions in real-world practice.

Eberlein B, Wigand S, Lewald H, Kochs E, Ring J, Biedermann T, Darsow U.

Immun Inflamm Dis.

Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma.

Aguilar-Pimentel A, Graessel A, Alessandrini F, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Russkamp D, Chaker A, Ollert M, Blank S, Gutermuth J, Schmidt-Weber CB.

PLoS One. 2017

Phenotypes of Atopic Dermatitis Depending on the Timing of Onset and Progression in Childhood.

Roduit C, Frei R, Depner M, Karvonen AM, Renz H, Braun-Fahrländer C, Schmausser-Hechfellner E, Pekkanen J, Riedler J, Dalphin JC, von Mutius E, Lauener RP; and the PASTURE study group, Hyvärinen A, Kirjavainen P, Remes S, Roponen M, Dalphin ML, Kaulek V, Ege M, Genuneit J, Illi S, Kabesch M, Schaub B, Pfefferle PI, Doekes G.

JAMA Pediatr. 2

Interaction of 7-Alkoxycoumarins with the Aryl Hydrocarbon Receptor.

Gargaro M, Epifano F, Fiorito S, Taddeo VA, Genovese S, Pirro M, Turco A, Puccetti P, Schmidt-Weber CB, Fallarino F.

J Nat Prod.

The value of teledermatology using a mobile app compared to conventional dermatology.

Zink A, Kolbinger A, Leibl M, Leon-Suarez I, Gloning J, Merkel C, Biedermann T, Ring J, Eberlein B.

Eur J Dermatol.

Component-resolved evaluation of the content of major allergens in therapeutic extracts for specific immunotherapy of honeybee venom allergy.

Blank S, Etzold S, Darsow U, Schiener M, Eberlein B, Russkamp D, Wolf S, Graessel A, Biedermann T, Ollert M, Schmidt-Weber CB.

Hum Vaccin Immunother.

Cytochrome P450s in human immune cells regulate IL-22 and c-Kit via an AHR feedback loop.

Effner R, Hiller J, Eyerich S, Traidl-Hoffmann C, Brockow K, Triggiani M, Behrendt H, Schmidt-Weber CB, Buters JT.

Sci Rep.

The shape of the microbiome in early life.

von Mutius E.

Nat Med.

Effects of structured patient education in adults with atopic dermatitis: Multicenter randomized controlled trial.

Heratizadeh A, Werfel T, Wollenberg A, Abraham S, Plank-Habibi S, Schnopp C, Sticherling M, Apfelbacher C, Biedermann T, Breuer K, Fell I, Fölster-Holst R, Heine G, Grimm J, Hennighausen L, Kugler C, Reese I, Ring J, Schäkel K, Schmitt J, Seikowski K, von Stebut E, Wagner N, Waßmann-Otto A, Wienke-Graul U, Weisshaar E, Worm M, Gieler U, Kupfer J; Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene (ARNE) Study Group.

J Allergy Clin Immunol.

Asthmatic/wheezing phenotypes in preschool children: Influential factors, health care and urban-rural differences.

Kutzora S, Weber A, Heinze S, Hendrowarsito L, Nennstiel-Ratzel U, von Mutius E, Fuchs N, Herr C; GME Study Group.

Int J Hyg Environ Health. 2017

The neonatal window of opportunity-early priming for life.

Renz H, Adkins BD, Bartfeld S, Blumberg RS, Farber DL, Garssen J, Ghazal P, Hackam DJ, Marsland BJ, McCoy KD, Penders J, Prinz I, Verhasselt V, von Mutius E, Weiser JN, Wesemann DR, Hornef MW.

J Allergy Clin Immunol.

Specific Surface Modifications of Silica Nanoparticles Diminish Inflammasome Activation and In Vivo Expression of Selected Inflammatory Genes.

Marzaioli V, Groß CJ, Weichenmeier I, Schmidt-Weber CB, Gutermuth J, Groß O, Alessandrini F.

Nanomaterials (Basel).

Pro-Inflammatory versus Immunomodulatory Effects of Silver Nanoparticles in the Lung: The Critical Role of Dose, Size and Surface Modification.

Alessandrini F, Vennemann A, Gschwendtner S, Neumann AU, Rothballer M, Seher T, Wimmer M, Kublik S, Traidl-Hoffmann C, Schloter M, Wiemann M, Schmidt-Weber CB.

Nanomaterials (Basel).

Exploring the associations between parent-reported biological indoor environment and airway-related symptoms and allergic diseases in children.

Weber A, Fuchs N, Kutzora S, Hendrowarsito L, Nennstiel-Ratzel U, von Mutius E, Herr C, Heinze S; GME Study Group.

Int J Hyg Environ Health.

Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate TH17-deviated acute contact dermatitis in human subjects.

Garzorz-Stark N, Lauffer F, Krause L, Thomas J, Atenhan A, Franz R, Roenneberg S, Boehner A, Jargosch M, Batra R, Mueller NS, Haak S, Groß C, Groß O, Traidl-Hoffmann C, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K.

J Allergy Clin Immunol. 2017

[Anaphylaxis caused by hymenoptera stings - Importance of instructions and training for emergency treatment by non medical personnel].

Welchering N, von Mutius E, Fuchs O.

MMW Fortschr Med. 2017

Asthmatic farm children show increased CD3+CD8low T-cells compared to non-asthmatic farm children.

Twardziok M, Schröder PC, Krusche J, Casaca VI, Illi S, Böck A, Loss GJ, Kabesch M, Toncheva AA, Roduit C, Depner M, Genuneit J, Renz H, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Schaub B; PASTURE Study Group:, Hyvärinen A, Karvonen AM, Kirjavainen PV, Remes S, Kaulek V, Dalphin ML, Ege M, Pfefferle PI, Doekes G.

Clin Immunol.